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Fluzoparib

更新时间：2024-07-17 15:06:29 采购访问：15次
常用名 氟唑帕利 CAS号 1358715-18-0
价格 $700.0/100mg $1300.0/250mg $2200.0/1g 纯度 98.0%
备货期 3天 库存 3
产品网页 https://www.dcchemicals.com/product_show-DC22228.html
 产品详情（用途，包装等）
Fluzoparib (SHR 3162) is a selective poly [ADP-ribose] polymerase 1 (PARP1) and poly [ADP-ribose] polymerase 2 inhibitor (PARP2), being developed by Jiangsu HengRui Medicine, for the treatment of cancer. PARP enzymes play a vital role in repair of DNA damage and maintaining genomic stability. Fluzoparib inhibits PARP enzymes and induces DNA-double strands breaks, G2/M arrest and apoptosis in homologous recombination repair (HR)-deficient cells. Clinical development for ovarian cancer, breast cancer, fallopian tube cancer, peritoneal cancer, gastric cancer and solid tumours is underway in China and Australia.

An orally available inhibitor of poly (ADP-ribose) polymerase (PARP) types 1 and 2, with potential antineoplastic activity. Upon oral administration, fluzoparib inhibits PARP 1 and 2 activity, which inhibits PARP-mediated repair of damaged DNA via the base excision repair (BER) pathway, enhances the accumulation of DNA strand breaks, promotes genomic instability, and leads to an induction of apoptosis. The PARP family of proteins catalyze post-translational ADP-ribosylation of nuclear proteins, which then transduce signals to recruit other proteins to repair damaged DNA. PARP inhibition may enhance the cytotoxicity of DNA-damaging agents and may reverse tumor cell chemoresistance and radioresistance.
供应商信息

DC Chemicals Limited 认证供应商

认证状态：已认证供应商
商品数：34963件
电话：58447131
地址：浦东新区金豫路100号
地区： 上海市 上海市 浦东新区
联系人：Tony Cao
联系人电话：13564518121
邮件：sales@dcchemicals.com
网址：http://www.dcchemicals.com
主要市场：
年贸易额：>1000万
外贸占销售比例：
主要合作伙伴：
D&C Chemicals provides a wide range of research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and Natural compounds for laboratory and scientific use.



D&C Chem has established a global network of thousands of customers from many research centers and Reagent companies in the USA, Europe and Japan.

We are the the official vendor of more than 500 universities and institutes including: Harvard University,Yale University,NIH/NCI, City of Hope ORG, PARTNERS ORG,John Hopkins University,Universit tsklinikum,Oxford University,Newcastle University,UNC,UCSF and many other universities and institutes. Our bioactive compounds received good feedback from our customers.





Our credo is committed to the adoption of different products, reliable quality, competitive prices and quality service to create value for customers.
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其他供应商价格：
2024-07-15 氟唑帕利（SHR-3162）
价格：需询单
2022-11-29 Fluzoparib
价格：￥需询单
2024-03-12 氟唑帕利（SHR-3162）
价格：￥1647.9
2022-05-12 Fluzoparib
价格：$需询单

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Fluzoparib价格为$700.0/100mg, 由Fluzoparib生产厂家DC Chemicals Limited提供，供应信息包括纯度，备货期/库存，供货能力等。>>移动MIP版：Fluzoparib _价格_生产厂家【DC Chemicals Limited】
标题：Fluzoparib - 生产厂家：DC Chemicals Limited 地址：https://www.chemsrc.com/Product/4321886.html

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