4-Piperidinamine, 1-[3-(2,3-dichlorophenyl)-1H-pyrazolo[3,4-b]pyrazin-6-yl]-4-methyl-
更新时间：2025-09-14 19:03:55
| 常用名 | 4-Piperidinamine, 1-[3-(2,3-dichlorophenyl)-1H-pyrazolo[3,4-b]pyrazin-6-yl]-4-methyl | CAS号 | 2160546-07-4 |
|---|---|---|---|
| 价格 | ￥需询单/1mg | 纯度 | 98.0% |
| 备货期 | 3天 | 库存 | 现货 |
| 产品详情（用途，包装等）
用途： IACS-13909 is a specific and potent allosteric inhibitor of SHP2 that suppresses the signaling of RTK/MAPK pathway and overcomes multiple mechanisms underlying osimertinib resistance. IACS-13909 potently impedes the proliferation of tumors with a broad spectrum of RTKs as the oncogenic driver. Importantly, in NSCLC models with acquired resistance to osimertinib, IACS-13909 administered as a single agent or in combination with osimertinib potently reduces tumor cell proliferation in vitro and in vivo. Together, our findings provide preclinical evidence for using a SHP2 inhibitor as a therapeutic strategy in acquired EGFR inhibitor-resistant NSCLC. 物理化学性质： CAS号：2160546-07-4 常用中文名：4-Piperidinamine, 1-[3-(2,3-dichlorophenyl)-1H-pyrazolo[3,4-b]pyrazin-6-yl]-4-methyl 常用英文名：4-Piperidinamine, 1-[3-(2,3-dichlorophenyl)-1H-pyrazolo[3,4-b]pyrazin-6-yl]-4-methyl 分子式：C17H18Cl2N6 分子量：377.27 密度：N/A 沸点：N/A 熔点：N/A 闪点：N/A 储存条件：-20°C |
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：IACS-13909
- 价格： ￥3294.9/10mg ￥1029.9/1mg ￥2059.9/5mg ￥6179.9/25mg
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
2881459338
复制
- 上海化源世纪贸易有限公司
- 上海市 上海市 普陀区
- 产品名：IACS-13909
- 价格：
- 纯度：98.0%
- 备货期：10天
- 联系人：徐经理
351666998
复制
13311869306
复制
查看所有供应商和价格请点击：
4-Piperidinamine, 1-[3-(2,3-dichlorophenyl)-1H-pyrazolo[3,4-b]pyrazin-6-yl]-4-methyl生产厂家