常用名 | GNE-9605 | CAS号 | 1536200-31-3 |
---|---|---|---|
价格 | ¥需询单/1mg | 纯度 | 98.0% |
备货期 | 3天 | 库存 | 现货 |
产品详情(用途,包装等)
用途: GNE-9605 is a highly potent, selective, and brain-penetrant LRRK2 inhibitor with IC50 of 19 nM.IC50 value:Target: LRRK2GNE-9605 retained excellent predicted human metabolic stability when assayed in human liver microsomes and hepatocytes. Inaddition, no reversible or time-dependent inhibition of any of the major CYP isoforms was observed. The demonstrated metabolic stability, brain penetration across multiple species, and selectivity of these inhibitors support their use in preclinical efficacy and safety studies. 物理化学性质: CAS号:1536200-31-3 常用中文名:GNE-9605 常用英文名:GNE-9605 分子式:C17H20ClF4N7O 分子量:449.834 密度:1.7±0.1 g/cm3 沸点:587.9±60.0 °C at 760 mmHg 熔点:N/A 闪点:309.4±32.9 °C 储存条件:2-8℃ |