咪唑立宾
更新时间：2023-01-11 16:41:20
| 常用名 | 咪唑立宾 | CAS号 | 50924-49-7 |
|---|---|---|---|
| 价格 | ￥需询单/1mg | 纯度 | 98.0% |
| 备货期 | 3天 | 库存 | 现货 |
| 产品详情（用途，包装等）
用途： Mizoribine(NSC 289637; HE 69; β-Bredinin) is an immunosuppressive agents (IC50=100 uM) that inhibit the proliferation of lymphocytes selectively, via inhibition of IMPDH.IC50 Value:Target: IMPDHin vitro: Unlike azathioprine, Mizoribine is not taken up by nucleic acids in the cell. Instead, after phosphorylation MZR-5 -monophosphate inhibits GMP synthesis by the antagonistic blocking of IMPDH (Ki = 10(-8)M) and GMP- synthetase (Ki =10(-5) M) [1]. Pretreatment of cells with MZR partially, but significantly, attenuates the expression of monocyte chemoattractant protein (MCP)-1 mRNA and protein, whereas the poly IC-induced expressions for the other functional molecules, such as CCL5, fractalkine and IL-8 were not influenced by MZR treatment [2].in vivo:MZR 150 mg was administered once a day. After 6 months, the remission rate was 72.7% (2 subjects achieved complete remission, and 9 partial remission). After 3 and 6 months, significant reductions (p 物理化学性质： CAS号：50924-49-7 常用中文名：咪唑立宾 常用英文名：Mizoribine 分子式：C9H13N3O6 分子量：259.216 密度：2.1±0.1 g/cm3 沸点：755.9±60.0 °C at 760 mmHg 熔点：>200ºC 闪点：410.9±32.9 °C 储存条件：库房通风,低温,干燥 |
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：咪唑立宾
- 价格： ￥61.9/10mg ￥123.9/50mg ￥230.9/100mg ￥460.9/250mg
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
- 上海阿摩尔生物科技有限公司
- 上海市 上海市 奉贤区
- 产品名：咪唑立宾
- 价格： ￥需询单/100mg ￥需询单/10mg ￥需询单/1g ￥需询单/250mg
- 纯度：98.0%
- 备货期：需询单
- 联系人：王汐瑶
- 武汉敬康恩生物医药科技有限公司
- 湖北省 武汉市 东西湖区
- 产品名：咪唑立宾
- 价格： ￥1.0/100g ￥1.0/500g
- 纯度：98.0%
- 备货期：1天
- 联系人：周经理
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参考价格：￥327.6/10mg