ZT-12-037-01
更新时间：2026-04-06 06:24:40
| 常用名 | ZT-12-037-01 | CAS号 | 2328073-61-4 |
|---|---|---|---|
| 价格 | ￥需询单/1mg | 纯度 | 98.0% |
| 备货期 | 3天 | 库存 | 现货 |
| 产品详情（用途，包装等）
用途： ZT-12-037-01 is a potent, selective, ATP-competitive STK19 inhibitor with IC50 of 20.04 nM measured as percentage of NRAS phosphorylation; shows similar IC50 of 23.96 and 27.94 nM for STK19WTWT STK19D89N respectively; displays extremely high kinase selectivity using KINOMEscan against a panel of 468 diverse kinases using an in vitro ATP-site competition binding assay at 1 uM; efficiently inhibits phosphorylation of NRAS in a dose- and time-dependent manner, inhibits NRAS activity in a dose-dependent manner but does not affect the levels of H3K9 methylation; effectively inhibits NRAS signaling, including the MEK-ERK and PI3K pathways in SK-MEL-2 and WM2032 cells (with NRASQ61R), but the inhibition was much less effective in A375 or UACC62 cells (with NRASWT), effectively inhibits cell growth and induces apoptosis of SK-MEL-2 and WM2032 melanoma cells. 物理化学性质： CAS号：2328073-61-4 常用中文名：ZT-12-037-01 常用英文名：ZT-12-037-01 分子式：C21H31N5O2 分子量：385.50 密度：N/A 沸点：N/A 熔点：N/A 闪点：N/A 储存条件：-20°C，密闭，干燥 |
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：ZT-12-037-01
- 价格： ￥205.9/1mg ￥2265.9/25mg ￥7209.9/100mg ￥需询单/1g
- 纯度：99.0%
- 备货期：1天
- 联系人：阿拉丁
2881459338
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- 武汉壹加壹生物科技有限公司
- 湖北省 武汉市 江夏区
- 产品名：ZT-12-037-01
- 价格： ￥需询单/1g ￥需询单/5g
- 纯度：98.0%
- 备货期：需询单
- 联系人：刘经理
673003916
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16602739303
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- 上海化源世纪贸易有限公司
- 上海市 上海市 普陀区
- 产品名：N2-环丙基-N4-(1-异丙基哌啶-4-基)-6,7-二甲氧基-2,4-二胺
- 价格：
- 纯度：98.0%
- 备货期：10天
- 联系人：徐经理
351666998
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13311869306
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