BDA-366
更新时间：2020-01-06 17:06:19
采购访问：18次
| 常用名 | BDA-366 | CAS号 | 1821496-27-8 |
|---|---|---|---|
| 价格 | $600.0/100mg $1100.0/250mg $2200.0/1g | 纯度 | 98.0% |
| 备货期 | 3天 | 库存 | 现货 |
| 产品网页 | http://www.dcchemicals.com/product_show-BDA_366.html | ||
| 产品详情（用途，包装等）
BDA-366 is a small-molecule Bcl2-BH4 domain antagonist, BDA-366, that binds BH4 with high affinity and selectivity. BDA-366-Bcl2 binding induces conformational change in Bcl2 that abrogates its antiapoptotic function, converting it from a survival molecule to a cell death inducer. BDA-366 suppresses growth of lung cancer xenografts derived from cell lines and patient without significant normal tissue toxicity at effective doses. mTOR inhibition upregulates Bcl2 in lung cancer cells and tumor tissues from clinical trial patients. Combined BDA-366 and RAD001 treatment exhibits strong synergy against lung cancer in vivo. |
DC Chemicals Limited
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商品数：34963件
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