常用名 | 阿格拉宾 | CAS号 | 84692-91-1 |
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价格 | ¥需询单/1mg | 纯度 | 98.0% |
备货期 | 3天 | 库存 | 询单 |
产品详情(用途,包装等)
用途: Arglabin is a sesquiterpene gamma-lactone is isolated from Artemisia glabella; anticancer natural compound.IC50 value:Target: anticancerin vitro: Arglabin-stimulated macrophages displayed a strong cytotoxic activity and the lowest doses (1.25 micrograms/mL and 0.125 micrograms/mL) induced a significant stimulation of cell mitochondrial metabolism, which correlated with [3H]TdR uptake by J774.1 cells under the same experimental conditions. Arglabin triggered the production of the three cytokines from J774-1 cells. However, the pattern of cytokine secretion differed to some extent, according to the methodology used for cytokine measurement: either traditional bioassay or specific immunoassay (ELISA) [1]. Arglabin exhibits antiexudative and antiproliferative properties on the models of acute aseptic inflammation caused by formalin, carrageenan, and histamine, and on the model of proliferative inflammation accompanying cotton-pellet granuloma [2]. Arglabin is able to reduce the proportion of AML stem cells (CD34+CD38-) in primary AML cells [3]. 物理化学性质: CAS号:84692-91-1 常用中文名:阿格拉宾 常用英文名:Arglabin 分子式:C15H18O3 分子量:246.302 密度:1.2±0.1 g/cm3 沸点:404.6±45.0 °C at 760 mmHg 熔点:102 °C 闪点:171.3±23.3 °C 储存条件:-20°C;避免光,加热 |