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甲磺酸多沙唑嗪

更新时间:2022-08-15 15:27:05

常用名 甲磺酸多沙唑嗪 CAS号 77883-43-3
价格 ¥需询单/1kg ¥需询单/1g ¥需询单/1mg ¥需询单/1ton 纯度 99.0%
备货期 需询单 库存 现货
 产品详情(用途,包装等)
用途:
Doxazosin mesylate(UK 33274) is a quinazoline-derivative that selectively antagonizes postsynaptic α1-adrenergic receptors.Target: α1-adrenergic receptorDoxazosin (mesylate) is the mesylate salt form of doxazosin, which is a long-lasting inhibitor of α1-adrenoceptors that is widely used to treat benign prostatic hyperplasia and lower urinary tract symptoms [1]. doxazosin may have a direct inhibitory effect on cholesterol synthesis independent of the LDL receptor. The inhibition of cholesterol synthesis by doxazosin may cause cells to compensate by upregulating the LDL receptor, thereby increasing the importation of lipoprotein cholesterol and reducing LDL cholesterol in the medium [2]. Doxazosin monotherapy was effective in eight of 12 patients (66.7%), and combined therapy with a beta-blocker was effective in 11 of 12 patients (91.7%). The mean pulse rate remained constant throughout therapy. Adverse reactions were minor and transient and occurred in only three patients. Urinary and plasma catecholamine levels tended to decrease or remained unchanged during doxazosin therapy [3].
物理化学性质:
CAS号:77883-43-3
常用中文名:甲磺酸多沙唑嗪
常用英文名:Doxazosin mesylate
分子式:C24H29N5O8S
分子量:547.581
密度:N/A
沸点:718ºC at 760 mmHg
熔点:275-277ºC
闪点:388ºC
储存条件:Desiccate at RT

供应商信息

裴申生物工程(上海)有限公司

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参考价格:$77/10mM*1mLinDMSO
其他供应商价格:
2022-02-19 甲磺酸多沙唑嗪
价格:¥153.9
2019-03-05 甲磺酸多沙唑嗪
价格:¥638.0
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价格:需询单
2018-10-19 甲磺酸多沙唑嗪
价格:¥需询单
2024-05-11 甲磺酸多沙唑嗪
价格:¥需询单
2017-09-11 甲基硫酸多沙唑嗪
价格:¥需询单
2017-06-20 甲磺酸多沙唑嗪
价格:¥需询单
2021-02-06 Doxazosin Mesylate
价格:¥439.0
2024-01-09 Doxazosin mesylate
价格:$需询单

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