常用名 | α-香附酮 | CAS号 | 473-08-5 |
---|---|---|---|
价格 | ¥需询单/20mg | 纯度 | 98.0% |
备货期 | 需询单 | 库存 | 询单 |
产品详情(用途,包装等)
用途: Alpha-cyperone is associated with the down-regulation of COX-2,IL-6,Nck-2,Cdc42 and Rac1, resulting in reduction of inflammation. which would be highly beneficial for treatment of inflammatory diseases such as AD.In vitro: The anti-inflammatory activity of alpha-cyperone is associated with the down-regulation of COX-2 and IL-6 via the negative regulation of the NFκB pathway in LPS-stimulated RAW 264.7 cells.[1]Alpha-Cyperone binds and interacts with tubulin and is capable of distinctly destabilizing microtubule polymerization. The effect of this interaction could result in reduction of inflammation which would be highly beneficial for treatment of inflammatory diseases such as AD. One microliter of alpha-Cyperone was dissolved in DMSO (1:1 v/v) and it was further diluted in double distilled water (ddH2O) to a final volume of 20 microliter. [2] 物理化学性质: CAS号:473-08-5 常用中文名:α-香附酮 常用英文名:alpha-Cyperone 分子式:C15H22O 分子量:218.335 密度:1.0±0.1 g/cm3 沸点:320.4±22.0 °C at 760 mmHg 熔点:N/A 闪点:142.8±13.2 °C 储存条件:-20°C |