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乳清酸

更新时间:2025-09-10 12:00:10

常用名 乳清酸 CAS号 65-86-1
价格 ¥80.0/25g ¥150.0/100g ¥500.0/500g 纯度 98.0%
备货期 2天 库存 5 kg
 产品详情(用途,包装等)
用途:
Orotic acid (OA) is an intermediate in pyrimidine metabolism.IC50 Value: Target: Nucleoside antimetabolite/analogin vitro: OA increases cell proliferation and decreases apoptosis in serum-starved SK-Hep1 hepatocellular carcinoma cells, which may ascribe to the inhibition of AMP-activated protein kinase (AMPK) phosphorylation and thus activation of mammalian target of rapamycin complex 1 (mTORC1) [1].in vivo: male Fischer 344 rats (130-150 g) to two-thirds PH in the absence or in the presence of OA (a 300-mg tablet of OA methyl ester implanted intraperitoneally at the time of two-thirds PH). treatment with OA resulted in a near-100% inhibition of RNR induced by two-thirds PH in rat liver, as monitored by enzyme activity and protein level [2]. The increases of hepatic OA and betaine levels in OA feeding rats was also found when compared to the normal rats [3]. Feeding 1% OA with diet decreased the phosphorylation of AMPK and increased the maturation of SREBP-1 and the expression of SREBP-responsive genes in the rat liver. OA-induced lipid accumulation was also completely inhibited by rapamycin. Mouse hepatocytes and mice were resistant to OA-induced lipogenesis because of little if any response in AMPK and downstream effectors [4].
物理化学性质:
CAS号:65-86-1
常用中文名:乳清酸
常用英文名:Orotic acid
分子式:C5H4N2O4
分子量:156.096
密度:1.8±0.1 g/cm3
沸点:656.9±65.0 °C at 760 mmHg
熔点:>300°C
闪点:351.1±34.3 °C
储存条件:室温

供应商信息

上海源叶生物科技有限公司

认证状态:未认证供应商
电话:61559134
地址:上海市松江区长塔路465号6幢
地区: 上海市 上海市 松江区
联系人:何喜莲
联系人电话:15921386130 021-61559134
邮件:3285254746@qq.com
网址:http://www.shyuanye.com
主要市场:国内
年贸易额:¥1000万-5000万
外贸占销售比例:
主要合作伙伴:
上海源叶生物科技有限公司是一家专门从事生物技术相关产品研发和销售的综合性生命科学公司,在全体员工的不懈努力和广大客户的大力支持下,公司迅速成长为一家拥有生物试剂部、实验部、生命科学仪器部以及技术服务部等部门的高新技术企业。 公司地址:上海市杨浦区黄兴路1999号2号楼8E 我们的理念: 客户至上、服务至真;质量第一、诚信为本
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参考价格:$66/10mM*1mLinDMSO
其他供应商价格:
2025-02-25 乳清酸(无水)(Orotic acid)
价格:¥需询单
2022-11-29 Orotic acid (6-Carboxyuracil)
价格:¥需询单
2022-02-19 乳清酸
价格:¥29.9
2017-08-06 乳清酸
价格:¥需询单
2024-06-15 乳清酸
价格:¥需询单
2018-01-09 乳清酸
价格:¥需询单
2024-12-23 Orotic Acid Anhydrous
价格:$21.5
2024-05-23 乳清酸
价格:¥需询单
2021-02-06 Orotic acid
价格:¥489.0

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