伏格列波糖
更新时间：2023-01-14 20:50:57
| 常用名 | 伏格列波糖 | CAS号 | 83480-29-9 |
|---|---|---|---|
| 价格 | ￥需询单/1kg ￥需询单/100g | 纯度 | 99.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情（用途，包装等）
用途： Voglibose is an N-substituted derivative of valiolamine, excellent inhibitory activity against α-glucosidases and its action against hyperglycemia and various disorders caused by hyperglycemia.Target: α-glucosidasesglibose can inhibit the intestinal α-glucosidases, which are responsible for the digestion of disaccharides such as maltose and sucrose, including maltase and sucrase. The Ki values of Voglibose for sucrase and maltase are about 106and 105 times smaller than the Km values for sucrose and maltose [1]. Voglibose (0.2 mg/kg) completely inhibits the insulin response to sucrose in rats. Voglibose (0.2 mg/kg) reduces the carbohydrate-induced increase in blood glucose in rats. Voglibose (0.2 mg/kg) reduces the carbohydrate-induced increase in blood glucose without causing sustained hypoglycemia in both normal and neonatal streptozotocin-induced diabetic rats [2]. Voglibose (0.001%) treatment increases GLP-1 secretion (Voglibose alone, 1.6-fold; Alogliptin plus Voglibose, 1.5-fold), while it decreases plasma glucose-dependent insulinotropic polypeptide (GIP) (Voglibose alone, 30%; Alogliptin plus voglibose, 29%) in prediabetic db/db mice after 3 weeks. Voglibose (0.001%) treatment decreases plasma DPP-4 activity by 15% in prediabetic db/db mice. Voglibose (0.001%) treatment increases plasma insulin by 1.8-fold and decreases plasma glucagon by 8% in prediabetic db/db mice [3]. 物理化学性质： CAS号：83480-29-9 常用中文名：伏格列波糖 常用英文名：Voglibose 分子式：C10H21NO7 分子量：267.276 密度：1.6±0.1 g/cm3 沸点：601.9±55.0 °C at 760 mmHg 熔点：162-163ºC 闪点：274.1±22.1 °C 储存条件：Store at -20°C |
- 黄石昊德医药科技有限公司
- 湖北省 黄石市 下陆区
- 产品名：伏格列波糖
- 价格：
- 纯度：98.0%
- 备货期：10天
- 联系人：李小姐
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：伏格列波糖
- 价格： ￥463.9/100mg ￥499.9/500mg ￥388.9/50mg ￥155.9/1ml
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
- 上海阿摩尔生物科技有限公司
- 上海市 上海市 奉贤区
- 产品名：伏格列波糖
- 价格： ￥需询单/100mg ￥需询单/10mg ￥需询单/1g ￥需询单/250mg
- 纯度：98.0%
- 备货期：需询单
- 联系人：王汐瑶
- 上海吉至生化科技有限公司
- 上海市 上海市 奉贤区
- 产品名：伏格列波糖
- 价格： ￥268.0/20mg
- 纯度：98.0%
- 备货期：2天
- 联系人：刘佳
- 上海化源世纪贸易有限公司
- 上海市 上海市 普陀区
- 产品名：伏格列波糖
- 价格：
- 纯度：98.0%
- 备货期：10天
- 联系人：徐经理
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参考价格：$84/10mM*1mLinWater