异维A酸
更新时间：2022-01-22 16:21:46
| 常用名 | 异维A酸 | CAS号 | 4759-48-2 |
|---|---|---|---|
| 价格 | ￥需询单/1kg ￥需询单/100g ￥需询单/100kg ￥需询单/1ton | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情（用途，包装等）
用途： Isotretinoin(13-cis-Retinoic acid) is a medication used for the treatment of severe acne. It was first developed to be used as a chemotherapy medication for the treatment of brain cancer, pancreatic cancer and more.Target: RAR/RXRIsotretinoin has been the most effective and long-lasting drug for the treatment of severe acne for more than 30 years and can achieve long-term remission in 70-80% of patients after a single course. The new evidence-based European S3-guideline recommends the use of Isotretinoin as a first-line medication for the treatment of severe papulopustular or conglobate acne, especially when prognostically unfavorable factors are present: family history of acne, early onset, marked seborrhea, localization on the trunk, scarring, psychosocial disability or persistent/late-type acne [1]. Five patients with pityriasis rubra pilaris were treated with isotretinoin from September 1982 through 1985. Isotretinoin at an average dose of 1.16 mg/kg/day for 16 to 24 weeks caused complete or almost complete clearing in four of the five patients [2]. isotretinoin produces significant anti-inflammatory effects by inhibition of monocyte and neutrophil chemotaxis across intact biologic barriers in vivo [3]. Isotretinoin 5 mg/day is effective in reducing the number of acne lesions, and improving patients dermatologic quality of life, with minimal adverse effects [4]. Clinical indications: Acne Toxicity: Isotretinoin is teratogenic. It also causes mucocutaneous side effects suck as cheilitis, dry skin, and dry eyes. 作用： 本品主要的作用为使囊状上皮角化过程正常化，减少皮脂细胞数目与皮脂合成，从而减轻丙酸杆菌型痤疮。用于治疗严重痤疮等症。 物理化学性质： CAS号：4759-48-2 常用中文名：异维A酸 常用英文名：Isotretinoin 分子式：C20H28O2 分子量：300.435 密度：1.0±0.1 g/cm3 沸点：462.8±14.0 °C at 760 mmHg 熔点：172-175 °C(lit.) 闪点：350.6±11.0 °C 储存条件：−20°C |
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：13-顺-视黄酸
- 价格： ￥29.9/100mg ￥42.9/1g ￥30.9/500mg ￥150.9/5g
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
- 上海吉至生化科技有限公司
- 上海市 上海市 奉贤区
- 产品名：13-顺-视黄酸
- 价格： ￥1298.0/1g ￥258.0/100mg
- 纯度：98.0%
- 备货期：1天
- 联系人：刘佳
- 上海化源世纪贸易有限公司
- 上海市 上海市 普陀区
- 产品名：(2Z,4E,6E,8E)-3,7-二甲基-9-(2,6,6-三甲基环己-1-烯-1-基)壬-2,4,6,8-四烯酸
- 价格：
- 纯度：98.0%
- 备货期：10天
- 联系人：徐经理
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参考价格：$66/10mM*1mLinDMSO