富马酸氯马斯汀
更新时间：2026-01-06 08:49:38
| 常用名 | 富马酸氯马斯汀 | CAS号 | 14976-57-9 |
|---|---|---|---|
| 价格 | ￥需询单/1kg | 纯度 | 99.0% |
| 备货期 | 1天 | 库存 | 现货 |
| 产品详情（用途，包装等）
用途： Clemastine Fumarate is a selective histamine H1 receptor antagonist with IC50 of 3 nM.Target: Histamine H1 ReceptorClemastine Fumarate inhibits histamine induced rise in [Ca2+]i in HL-60 cells with an IC50 of 3 nM as compared with that of chlorpheniramine or diphenhydramine with IC50 values of 20 nM and 100 nM, respectively [1]. Clemastine showed a first-pass reduction in the extent of absorption, with oral bioavailability calculated as 39.2 +/- 12.4%. Extravascular distribution of drug was suggested by the high volume of distribution (799 +/- 315 L) and low Cmax (0.577 +/- 0.252 ng/mL/mg) observed at 4.77 +/- 2.26 hours after administration, and by the biphasic decline in plasma concentration. The terminal elimination half-life (t1/2) of clemastine was 21.3 +/- 11.6 hours. Steady-state concentrations of clemastine were consistent with linear pharmacokinetic processes, and clearance was unaffected by age in the range studied, or by race [2]. 物理化学性质： CAS号：14976-57-9 常用中文名：富马酸氯马斯汀 常用英文名：Clemastine fumarate 分子式：C25H30ClNO5 分子量：459.962 密度：1.097 g/cm3 沸点：116 °C / 24mmHg 熔点：61 °C 闪点：211ºC 储存条件：Store at RT |
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：Clemastine Fumarate
- 价格： ￥146.9/100mg ￥227.9/250mg ￥363.9/500mg ￥562.9/1g
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
- 上海阿摩尔生物科技有限公司
- 上海市 上海市 奉贤区
- 产品名：富马酸氯马斯汀
- 价格： ￥需询单/100mg ￥需询单/1g ￥需询单/250mg ￥需询单/25mg
- 纯度：98.0%
- 备货期：需询单
- 联系人：王汐瑶
- 上海化源世纪贸易有限公司
- 上海市 上海市 普陀区
- 产品名：富马酸氯马斯汀
- 价格：
- 纯度：98.0%
- 备货期：10天
- 联系人：徐经理
- 广东翁江化学试剂有限公司
- 广东省 韶关市 翁源县
- 产品名：富马酸氯马斯汀
- 价格： ￥2200.0/5g ￥640.0/1g
- 纯度：98.0%
- 备货期：需询单
- 联系人：朱丽丹
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参考价格：￥273/100mg