| 常用名 | 己酮可可碱 | CAS号 | 6493-05-6 |
|---|---|---|---|
| 价格 | ¥需询单/1000kg | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情(用途,包装等)
用途: Pentoxifylline is a competitive nonselective phosphodiesterase inhibitor.Target: PDEPentoxifylline is a competitive nonselective phosphodiesterase inhibitor which raises intracellular cAMP, activates PKA, inhibits TNF and leukotriene synthesis, and reduces inflammation and innate immunity. In addition, pentoxifylline improves red blood cell deformability, reduces blood viscosity and decreases the potential for platelet aggregation and thrombus formation. Pentoxifylline is also an antagonist at adenosine 2 receptors [1]. Pentoxifylline is generally well tolerated. Based on the totality of the available evidence, it is possible that pentoxifylline could have a place in the treatment of IC as a means of improving walking distance and as a complimentary treatment assuming all other essential measures such as lifestyle change, exercise and treatment for secondary prevention have been taken into account [2]. Pentoxifylline reduce AST and ALT levels and may improve liver histological scores in patients with NALFD/NASH, but did not appear to affect cytokines. Large, prospective, and well-designed randomized, controlled studies are needed to address this issue [3]. 物理化学性质: CAS号:6493-05-6 常用中文名:己酮可可碱 常用英文名:Pentoxifylline 分子式:C13H18N4O3 分子量:278.307 密度:1.3±0.1 g/cm3 沸点:531.3±56.0 °C at 760 mmHg 熔点:98-100°C 闪点:275.1±31.8 °C 储存条件:Store at RT |