| 常用名 | 芍药内酯苷 | CAS号 | 39011-90-0 |
|---|---|---|---|
| 价格 | ¥800.0/20mg | 纯度 | 96.0% |
| 备货期 | 1天 | 库存 | 900 mg |
| 产品详情(用途,包装等)
用途: Albiflorin is a major constituent contained in peony root; possesses therapeutic potential for neurodegenerative diseases.IC50 value:Target: in vitro: Albiflorin significantly ameliorated Glu-induced reduction of cell viability, nuclear and mitochondrial apoptotic alteration, reactive oxygen species accumulation, and B-cell lymphoma 2 (Bcl-2)/Bax ratio. Albiflorin also enhanced phosphorylation of AKT and its downstream element glycogen synthase kinase-3β, and this effect was abrogated by the AKT inhibitor LY294002 [1]. in vivo: Mice were exposed to X-ray radiation (400 Roentgen), and both mice and rabbits were intraperitoneally injected with cyclophosphamide (100.0 mg/kg) and cytarabine chloride (92.7 mg/kg), respectively, for 3 days to induce myelosuppression. Albiflorin was subsequently administrated intravenously at low (15.0 mg/kg for mice, 6.00 mg/kg for rabbits), intermediate (30.0 mg/kg for mice, 12.0 mg/kg for rabbits) and high (60.0 mg/kg for mice, 24.0 mg/kg for rabbits) doses, as well as orally (60.0 mg/kg for mice, 24.0 mg/kg for rabbits) for 7 days. Shenqi tablets were used as positive controls (oral administration of 936.0 mg/kg for mice, 336.0 mg/kg for rabbits). The administration of Albiflorin significantly ameliorated myelosuppression in all cases [2]. 物理化学性质: CAS号:39011-90-0 常用中文名:芍药内酯苷 常用英文名:albiflorin 分子式:C23H28O11 分子量:480.462 密度:1.6±0.1 g/cm3 沸点:722.1±60.0 °C at 760 mmHg 熔点:N/A 闪点:248.9±26.4 °C 储存条件:?20°C |