泽泻醇B醋酸酯
更新时间：2025-09-23 17:23:40
| 常用名 | 泽泻醇B乙酸酯 | CAS号 | 26575-95-1 |
|---|---|---|---|
| 价格 | ￥750.0/20mg | 纯度 | 98.0% |
| 备货期 | 1天 | 库存 | 900 mg |
| 产品详情（用途，包装等）
用途： Alisol B 23-acetate, a natural triterpenoid, produces protective effects against EE-induced cholestasis, due to FXR-mediated gene regulation.IC50 Value:Target: Anti-hepatotoxic natural product. In vitro: Alisol-B 23-acetate has an effect on FXR activation in a dose-dependent manner using luciferase reporter assay in HepG2 cells [3].In vivo: In alisol B 23-acetate-treated mice, the changes in transporters and enzymes, as well as ameliorative liver histology were abrogated by FXR antagonist guggulsterone [1]. Alisol B 23-acetate treatment in a dose-dependent manner resulted in protection against hepatotoxicity induced by CCl4via FXR activation. Through FXR activation, alisol B 23-acetate promoted hepatocyte proliferation via an induction in hepatic levels of FoxM1b, Cyclin D1 and Cyclin B1. Alisol B 23-acetate also reduced hepatic bile acids through a decrease in hepatic uptake transporter Ntcp, bile acid synthetic enzymes Cyp7a1, Cyp8b1, and an increase in efflux transporter Bsep, Mrp2 expression. In addition, alisol B 23-acetate induced the expression of STAT3 phosphorylation, and STAT3 target genes Bcl-xl and SOCS3, resulting in decreased hepatocyte apoptosis [2]. 物理化学性质： CAS号：26575-95-1 常用中文名：泽泻醇B乙酸酯 常用英文名：Alisol B 23-acetate 分子式：C32H50O5 分子量：514.736 密度：1.1±0.1 g/cm3 沸点：590.7±50.0 °C at 760 mmHg 熔点：N/A 闪点：179.9±23.6 °C 储存条件：2~8℃ |
- 上海化源世纪贸易有限公司
- 上海市 上海市 普陀区
- 产品名：23-乙酰泽泻醇B
- 价格：
- 纯度：99.8%
- 备货期：10天
- 联系人：徐经理
- 云南西力生物技术股份有限公司
- 云南省 昆明市 盘龙区
- 产品名：泽泻醇B单醋酸酯
- 价格： ￥需询单/5mg
- 纯度：98.0%
- 备货期：10天
- 联系人：郑雪平
- 四川恒诚致远生物科技有限公司
- 四川省 成都市 温江区
- 产品名：23-乙酰泽泻醇B
- 价格： ￥需询单/5mg ￥需询单/20mg ￥需询单/100mg ￥需询单/1g
- 纯度：98.0%
- 备货期：需询单
- 联系人：张半夏
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：乙酸泽泻醇B
- 价格： ￥720.9/10mg ￥1441.9/25mg ￥484.9/5mg ￥4016.9/100mg
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
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参考价格：$158/10mM*1mLinDMSO