常用名 | 柯诺辛 | CAS号 | 6877-32-3 |
---|---|---|---|
价格 | ¥需询单/20mg | 纯度 | 98.0% |
备货期 | 1天 | 库存 | 询单 |
产品详情(用途,包装等)
用途: Corynoxine is an enantiomer of Corynoxine B; induces autophagy in different neuronal cell lines, including N2a and SHSY-5Y cells.IC50 value:Tareget: Autophagy inducerIn vivo, Cory promotes the formation of autophagosomes in the fat bodies of Drosophila. By inducing autophagy, Cory promotes the clearance of wild-type and A53T α-syn in inducible PC12 cells. Interestingly, different from its enantiomer Cory B, Cory induces autophagy through the Akt/mTOR pathway as evidenced by the reduction in the levels of phospho-Akt, phospho-mTOR and phospho-p70 S6 Kinase [1]. Corynoxine significantly decreased locomotor activity after oral administration to mice [2]. 物理化学性质: CAS号:6877-32-3 常用中文名:柯诺辛 常用英文名:Corynoxine 分子式:C22H28N2O4 分子量:384.469 密度:1.2±0.1 g/cm3 沸点:560.8±50.0 °C at 760 mmHg 熔点:166-168ºC 闪点:293.0±30.1 °C 储存条件:-20°C |