咪达那新
更新时间：2025-08-31 15:09:59
| 常用名 | 咪达那新 | CAS号 | 170105-16-5 |
|---|---|---|---|
| 价格 | ￥需询单/1kg | 纯度 | 99.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品网页 | http://www.core-tech.com.cn/ | ||
| 产品详情（用途，包装等）
用途： Imidafenacin(KRP-197; ONO-8025) is a potent and selective inhibitor of M3 receptors with Kb of 0.317 nM; less potent for M2 receptors(IC50=4.13 nM).IC50 value: 0.3 nM(M3) [1]in vitro: KRP-197 showed equipotent anti-M2 and anti-M3 activity and decreased subtype-selectivity [1]. in vivo: Intraduodenal administration of KRP-197 (0.04±0.30 mg/kg) inhibited bladder contraction dose-dependently, and the ED30 value was 0.11 mg/kg. The inhibitory action of KRP-197 on the bladder contraction was 19 times as potent as that of oxybutynin. KRP-197 showed preventive action againstthe decrease in bladder capacity induced by carbachol(ED50 0.074 mg/kg, intragastric administration), andthe potency of the inhibitory action was 15-fold greaterthan that of oxybutynin [1]. The learning-inhibitory doses of intravenous oxybutynin hydrochloride and tolterodine tartrate were 0.3 and 3 mg/kg in sham-operated rats and 0.1 and 1 mg/kg in nbM-lesioned rats, respectively. Thus, the learning impairments by those antimuscarinics were more sensitive in nbM-lesioned rats than in sham-operated rats. On the other hand, intravenous administration of imidafenacin had no influence on learning in either case of the rats. In normal rats, however, intracerebroventricular administration of imidafenacin impaired learning to the same degree as that of oxybutynin hydrochloride [2]. 物理化学性质： CAS号：170105-16-5 常用中文名：咪达那新 常用英文名：Imidafenacin 分子式：C20H21N3O 分子量：319.400 密度：1.1±0.1 g/cm3 沸点：579.7±50.0 °C at 760 mmHg 熔点：N/A 闪点：304.4±30.1 °C 储存条件：2-8℃ |
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：咪唑啉
- 价格： ￥399.9/100mg ￥1999.9/1g ￥699.9/250mg ￥582.9/1ml
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
2881459338
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- 上海阿摩尔生物科技有限公司
- 上海市 上海市 奉贤区
- 产品名：咪达那新
- 价格： ￥需询单/100mg ￥需询单/10mg ￥需询单/1g ￥需询单/250mg
- 纯度：98.0%
- 备货期：需询单
- 联系人：王汐瑶
3623107365
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- 苏州市森菲达化工有限公司
- 江苏省 苏州市 相城区
- 产品名：咪达那新
- 价格： ￥需询单/200kg
- 纯度：98.0%
- 备货期：需询单
- 联系人：程经理
3912721726
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18796480002
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- 上海化源世纪贸易有限公司
- 上海市 上海市 普陀区
- 产品名：咪达那新
- 价格：
- 纯度：98.0%
- 备货期：10天
- 联系人：徐经理
351666998
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133 1186 9306
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参考价格：$79/10mM*1mLinDMSO