常用名 | 2-氰基-3,12-二氧代齐墩果-1,9-二烯-28-酸 | CAS号 | 218600-44-3 |
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价格 | ¥需询单/1kg | 纯度 | 98.0% |
备货期 | 需询单 | 库存 | 现货 |
产品详情(用途,包装等)
产品供应 产品名称: CDDO CAS: 218600-44-3 公司名称: 广州牌牌生物科技有限公司 联系姓名: 李金菊 联系电话: 13925170663 联系传真: 电子邮件: LJJ_PI@163.com 【详细描述】: - CAS NO. 218600-44-3 英文品名 Bardoxolone 中文品名 Bardoxolone 分子式 C31H41NO4 分子量 491.66 规格/纯度 >98% 供应能力 可提供公斤级别
别名 CDDO; RTA 401; RTA401; RTA-401 产品简述 Bardoxolone(RTA 402)是抗氧化炎症调节剂(AIM)的先导化合物,此类AIM是转录因子Nrf2诱导剂。 详细说明 Bardoxolone(RTA 402) is the lead molecule in Reata's portfolio of Antioxidant Inflammation Modulators (AIMs). The AIMs are potent inducers of the tranion factor Nrf2. IC50 value: Target: Nrf2 Nrf2 is an an important biological target that controls the production of many of the body's antioxidant and detoxification enzymes. Because oxidative stress and inflammation occur throughout the course of chronic kidney disease (CKD) and are known to contribute to loss of kidney function, agents that activate the Nrf2 pathway in patients with CKD may provide a novel method for preserving or improving kidney function. Bardoxolone methyl is currently being investigated as a potential oral once-a-day treatment for CKD. 更多
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