4-Hydroxy-2-quinolones. 167*. Study of the reaction of ethyl 1-alkyl-substituted 4-hydroxy-2-oxo-1, 2-dihydroquinoline-3-carboxylates with phosphorus oxychloride
IV Ukrainets, NL Bereznyakova, AA Davidenko…
文献索引：Ukrainets; Bereznyakova; Davidenko; Slobodzian Chemistry of Heterocyclic Compounds, 2009 , vol. 45, # 8 p. 952 - 956
Prolonged treatment of ethyl 1-alkyl-4-hydroxy-2-oxo-1, 2-dihydroquinoline-3-carboxylates with refluxing phosphorus oxychloride gives not only the target 4-chloro derivatives but is also accompanied by a marked loss of the 1-N-alkyl groups to form the side product 2, 4- dichloro-3-ethoxycarbonylquinoline.
