Reaction of secondary and tertiary aliphatic halides with aromatic aldehydes mediated by chromium (II): a selective cross-coupling of alkyl and ketyl radicals
LA Wessjohann, G Schmidt, HS Schrekker
文献索引：Wessjohann, Ludger A.; Schmidt, Gisela; Schrekker, Henri S. Tetrahedron, 2008 , vol. 64, # 9 p. 2134 - 2142
Takai–Utimoto reactions with secondary and tertiary aliphatic halides usually failed according to previous reports. Now, significant improvements could be achieved, and especially secondary aliphatic halides can be coupled to aromatic aldehydes in yields of up to> 95%. A variety of processes are competing with the desired one, and thus conditions must be adapted to the nature of the aldehyde as well as the aliphatic halide used, as the ...
