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The Journal of Organic Chemistry

Carbonylation of aryllithium reagents in the presence of alkyl halides: one-pot synthesis of diarylalkyl carbinols and derivatives

NS Nudelman, AA Vitale

文献索引:Nudelman, N. Sbarbati; Vitale, Arturo A. Journal of Organic Chemistry, 1981 , vol. 46, # 22 p. 4625 - 4626

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被引用次数: 45

摘要

Summary: The carbonylation of ArLi (Ar= Ph, o-anisyl) in the presence of alkyl bromides affords diarylalkylcarbinols in good yields. The reaction may be used to obtain alcohols functionalized in the alkyl chain; it can also be adapted to afford substituted tetrahydrofurans.