Highly potent inhibitors of methionine aminopeptidase-2 based on a 1, 2, 4-triazole pharmacophore

…, WC Xiong, Y Yamamoto, K Yamashita…

文献索引：Joshua, C. P.; Presannan, E.; Thomas, Saramma K. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, # 7 p. 649 - 651

全文：HTML全文

被引用次数: 51

摘要

... Journal of ... Departments of Medicinal Chemistry, Enzymology, Oncology, and Structural Biology, GlaxoSmithkline, King of Prussia, Pennsylvania 19406. J. Med. Chem. ... Table 1. SAR for 8 × 12 Triazole Array. cmpd, R1, R2, MetAP2 K i,app a (nM), cmpd, R1, R2, MetAP2 K i,app a (nM ...