Journal of the American Chemical Society

The Reaction of Certain Nitriles with Grignard Reagents1

FF Blicke, EP Tsao

文献索引：Blicke; Tsao Journal of the American Chemical Society, 1953 , vol. 75, p. 5587,5589

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被引用次数: 11

摘要

In a number of instances it has been found that a nitrile reacted with sodium and an alcoh~ l,~-~ with potassium hydroxidelo or with sodamide"-ls in such a manner that the cyano group was replaced by hydrogen. A few examples have also been reported in which the same type of cleavage was produced by a Grignard reagent. Thus triphenylacetonitrile reacted with benzylmagnesium chloride to produce triphe~~ ylmethane'~; dibenzylmalononitrile and ...