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Synlett

The microwave assisted nucleophilic substitution of 4-hydroxy-6-methyl-2 (1H)-pyridones

D Heber, EV Stoyanov

文献索引:Heber, Dieter; Stoyanov, Edmont V. Synlett, 1999 , # 11 p. 1747 - 1748

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被引用次数: 9

摘要

Abstract: The condensation of 4-hydroxy-6-methyl-2 (1H)-pyridones 1 with araliphatic amino compounds 2 gives rise to the 4-alkylamino-6-methyl-2 (1H)-pyridones 3. Irradiation using an ordinary domestic microwave oven provides a fast and simple method for their preparation. However, under the conditions used, aliphatic and aromatic amines gave no reaction. Key words: 4-alkylamino-6-methyl-2 (1H)-pyridones, microwave irradiation, ...