We have recently reported the regioselective electrophilic trifluoromethylation of substituted anilines and acetanilides in HF/SbF 5 in the presence of carbon tetrachloride. 6 Under the reaction conditions, the electrophile 'CCl 3 + ' obtained from CCl 4 , reacts with the N- or O-protonated substrate, the halogen exchange being completed by treatment of the reaction mixture with HF/pyridine. ... Hydroxylation of indoles with H 2 O 2 in superacids yields monohydroxy ...
