Synthesis of Quinazolinones from Alcohols via Laccase??Mediated Tandem Oxidation

…, S Ghasemi, Z Habibi, MA Faramarzi

文献索引：Heidary, Marjan; Khoobi, Mehdi; Ghasemi, Sabrieh; Habibi, Zohreh; Faramarzi, Mohammad Ali Advanced Synthesis and Catalysis, 2014 , vol. 356, # 8 p. 1789 - 1794

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被引用次数: 14

摘要

Abstract: This paper describes the synthesis of quinazolinones via a tandem reaction using the laccasemediator system under mild conditions. The procedure involved the laccase- catalyzed oxidation of alcohols to the corresponding aldehydes, followed by cyclocondensation with isatoic anhydride and a number of amines to afford 2, 3- dihydroquinazolin-4 (1H)-ones, which were further oxidized to quinazolinones in useful ...