Diastereoselective inter-and intramolecular pinacol coupling of aldehydes promoted by monomeric titanocene (III) complex Cp2TiPh

…, R Hattori, T Miwa, Y Nakagai, T Kubota…

文献索引：Yamamoto; Hattori; Miwa; Nakagai; Kubota; Okamoto; Itoh Journal of Organic Chemistry, 2001 , vol. 66, # 11 p. 3865 - 3870

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被引用次数: 59

摘要

A monomeric titanocene (III) derivative, Cp2TiPh, effectively promoted the pinacol coupling of both an aromatic aldehyde, benzaldehyde, and an aliphatic aldehyde, 3- phenylpropionaldehyde. The same reactive complex was successfully generated by a catalytic amount of a precursor, Cp2Ti (Ph) Cl, and its stoichiometric amount of Zn. The Cp2TiPh-catalyzed pinacol coupling of benzaldehyde derivatives and aliphatic aldehydes ...