3-Phenyl-4-hydroxyquinolin-2 (1H)-ones: potent and selective antagonists at the strychnine-insensitive glycine site on the N-methyl-D-aspartate receptor complex

…, JH Wikel, DO Calligaro, PJ O'Malley

文献索引：McQuaid; Smith; Lodge; Pralong; Wikel; Calligaro; O'Malley Journal of Medicinal Chemistry, 1992 , vol. 35, # 18 p. 3423 - 3425

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被引用次数: 62

摘要

(2) Wong, EHF; Kemp, JA Sites for antagonism on the N-methybaspartate receptor channel complex. Annu. Rev. Pharmacol. Tozicol. 1991, 31, 401-425.(3)(a) Johnston, JW; Ascher, P. Glycine potentiates the NMDA response in cultured mouse brain neurons. Nature 1987, 325, 529-531.(b) Kleckner, NW; Dingledme, R. Requirement for glycine in activation of NMDA- receptors expressed in Xeno-pus oocytes. Science 1988, 241, 835-837.(4)(a) Fletcher, EJ; ...