A facile method for deprotection of trityl ethers using column chromatography

AK Pathak, V Pathak, LE Seitz, KN Tiwari, MS Akhtar…

文献索引：Pathak, Ashish K.; Pathak, Vibha; Seitz, Lainne E.; Tiwari, Kamal N.; Akhtar, Mohammad S.; Reynolds, Robert C Tetrahedron Letters, 2001 , vol. 42, # 44 p. 7755 - 7757

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被引用次数: 24

摘要

A mild, efficient and inexpensive detritylation method is reported that uses trifluoroacetic acid on a silica gel column to obtain pure, detritylated compounds in one-step. This method is applicable to acid stable as well as acid sensitive compounds with only slight alterations in the procedure. Nineteen examples are given.