Organic process research & development

An efficient synthesis of 2-quinoxalinecarboxylic acid

AE Harms

文献索引：Harms, Arthur E. Organic Process Research and Development, 2004 , vol. 8, # 4 p. 666 - 669

全文：HTML全文

被引用次数: 11

摘要

Development of a cost efficient and scaleable process for 2-quinoxalinecarboxylic acid is described. The primarily goals of the development work were to improve the overall yield of the process, to minimize the use of environmentally unacceptable materials, and to obtain a material with a high level of purity. A variety of approaches were examined, and the most efficient method was a condensation of o-phenylenediamine with a monosaccharide ...