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5-Thiol-7-hydroxy-1-γ-triazolo [d] pyrimidine1, 2

CT Bahner, DE Bilancio

文献索引:Bahner; Bilancio Journal of the American Chemical Society, 1953 , vol. 75, p. 6038

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被引用次数: 5

摘要

been reported to be a strong inhibitor of the growth of Streptococcus faecalis R. 3 but not of Adenocarci-nomu 755.* The closely related compound having an hydroxy group in place of the 7-amino group has been prepared as described below. It produces a 65% reduction in the growth of L. casei at a concentration of 0.005 mg./ml. 6 The effect can be reversed by pteroylglutamic acid or adenine. The results of screening against various tumors are to be ...