前往化源商城

举例 :可输入Filippa Pettersson 或者 Cancer Res. 75(6) , 1102-12, (2015) 或者10.1002/anie.201600521

Tetrahedron letters

Metal-halogen exchange-initiated cyclization of iodo carbonyl compounds

MP Cooke, IN Houpis

文献索引：Cooke, Manning P.; Houpis, Ioannis N. Tetrahedron Letters, 1985 , vol. 26, # 41 p. 4987 - 4990

全文：HTML全文

被引用次数: 47

摘要

Abstract The feasibility of constructing carbocycles through the metal-halogen exchange- initiated cyclization reactions of iodoketones and other carboxyl derivatives has been studied. With saturated primary iodides, cyclization predominates when deactivated ketones are employed.

叔丁基锂结构式

~79%

3-isopropyl-2,2-dimethyl-heptan-3-ol结构式

3-isopropyl-2,2...

2-甲基-3-庚酮结构式

2-甲基-3-庚酮

1-(丙-2-基)环戊烷-1-醇结构式

1-(丙-2-基)环戊烷-1-醇

5-氯戊醛结构式

~%

1-(丙-2-基)环戊烷-1-醇结构式

1-(丙-2-基)环戊烷-1-醇

7-Chloro-2-methyl-3-heptanone结构式

7-Chloro-2-meth...

~%

1-(丙-2-基)环戊烷-1-醇结构式

1-(丙-2-基)环戊烷-1-醇

N,N-diethyl-6-iodohexanamide结构式

N,N-diethyl-6-i...

~5%

Caproic acid diethylamide结构式

Caproic acid di...

环己酮结构式

5-氯戊醛结构式

~%

6-chlorohexan-2-ol结构式

6-chlorohexan-2-ol

5-碘戊酸乙酯结构式

5-碘戊酸乙酯

~%

1-丁基-1-环戊醇结构式

1-丁基-1-环戊醇

环戊酮结构式

5,5-dimethoxy-1-iodo-1(Z)-pentene结构式

5,5-dimethoxy-1...

~%

2,2-dimethylhept-6-en-3-ol结构式

2,2-dimethylhep...

叔丁基锂结构式

(Z)-5-iodo-4-pentenal结构式

(Z)-5-iodo-4-pe...

~20%

环戊-2-烯醇结构式

环戊-2-烯醇

2,2-dimethylhept-6-en-3-ol结构式

2,2-dimethylhep...

8-iodooctan-4-one结构式

8-iodooctan-4-one

~50%

4-辛酮结构式

1-n-丙基环戊醇结构式

1-n-丙基环戊醇

未登录结构式

5-氯戊醛结构式

~%

1-n-丙基环戊醇结构式

1-n-丙基环戊醇

8-chlorooctan-4-ol结构式

8-chlorooctan-4-ol

~%

1-n-丙基环戊醇结构式

1-n-丙基环戊醇

8-chlorooctan-4-one结构式

8-chlorooctan-4-one

~%

1-n-丙基环戊醇结构式

1-n-丙基环戊醇

叔丁基锂结构式

8-iodooctan-4-one结构式

8-iodooctan-4-one

~49%

4-辛酮结构式

1-n-丙基环戊醇结构式

1-n-丙基环戊醇

详细

8-chlorooctan-4-ol结构式

8-chlorooctan-4-ol

~%

8-chlorooctan-4-one结构式

8-chlorooctan-4-one

未登录结构式

~86%

methyl-butyl-γ-butenyl-carbinol结构式

methyl-butyl-γ-...

1-methylcyclopent-2-en-1-ol结构式

1-methylcyclope...

6-iodo-5(Z)-hexen-2-ol结构式

6-iodo-5(Z)-hex...

~%

1-methylcyclopent-2-en-1-ol结构式

1-methylcyclope...

5,5-dimethoxy-1-iodo-1(Z)-pentene结构式

5,5-dimethoxy-1...

~%

1-methylcyclopent-2-en-1-ol结构式

1-methylcyclope...

(Z)-5-iodo-4-pentenal结构式

(Z)-5-iodo-4-pe...

~%

1-methylcyclopent-2-en-1-ol结构式

1-methylcyclope...

正丁基锂结构式

未登录结构式

~86%

methyl-butyl-γ-butenyl-carbinol结构式

methyl-butyl-γ-...

1-methylcyclopent-2-en-1-ol结构式

1-methylcyclope...

叔丁基锂结构式

未登录结构式

~19%

2,2,3-trimethyl-6-hepten-3-ol结构式

2,2,3-trimethyl...

1-methylcyclopent-2-en-1-ol结构式

1-methylcyclope...

5-氯戊醛结构式

~%

8-chlorooctan-4-one结构式

8-chlorooctan-4-one

5-氯戊醛结构式

~%

1-苯基-1-环戊醇结构式

1-苯基-1-环戊醇

5-chloro-1-phenylpentan-1-one结构式

5-chloro-1-phen...

~%

1-苯基-1-环戊醇结构式

1-苯基-1-环戊醇

1-phenyl-5-chloropentan-1-ol结构式

1-phenyl-5-chlo...

~%

1-苯基-1-环戊醇结构式

1-苯基-1-环戊醇

1-iodo-5-hexanone结构式

1-iodo-5-hexanone

~20%

2,2,3-trimethylheptan-3-ol结构式

2,2,3-trimethyl...

2-己酮结构式

1-甲基环戊醇结构式

1-甲基环戊醇

5-氯戊醛结构式

~%

2,2,3-trimethylheptan-3-ol结构式

2,2,3-trimethyl...

6-氯-2-己酮结构式

~%

2,2,3-trimethylheptan-3-ol结构式

2,2,3-trimethyl...

6-chlorohexan-2-ol结构式

6-chlorohexan-2-ol

~%

2,2,3-trimethylheptan-3-ol结构式

2,2,3-trimethyl...

1-iodo-5-hexanone结构式

1-iodo-5-hexanone

叔丁基锂结构式

~20%

2,2,3-trimethylheptan-3-ol结构式

2,2,3-trimethyl...

2-己酮结构式

详细

未登录结构式

~69%

环戊酮结构式

Soluble Lanthanide Salts (LnCl3⋅ 2 LiCl) for the Improved Ad...

[Krasovskiy, Arkady; Kopp, Felix; Knochel, Paul Angewandte Chemie - International Edition, 2006 , vol. 45, # 3 p. 497 - 500]

Olefinic Cyclizations. VI. Formolysis of Some Branched-Chain...

[Johnson,W.S.; Owyang,R. Journal of the American Chemical Society, 1964 , vol. 86, p. 5593 - 5598]

The Effect of Cyclopentane and Cyclohexane Rings on the Reac...

[Skinner; Florentine Journal of the American Chemical Society, 1954 , vol. 76, p. 3200,3201]

Olefinic Cyclizations. VI. Formolysis of Some Branched-Chain...

[Johnson,W.S.; Owyang,R. Journal of the American Chemical Society, 1964 , vol. 86, p. 5593 - 5598]

Some studies on the solvolysis of 1-chloro-1-alkyl cycloalka...

[Ranganayakulu, K.; Vasumathi Devi, M.; Balaji Rao, R.; Rajeswari, K. Canadian Journal of Chemistry, 1980 , vol. 58, # 14 p. 1484 - 1489]