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举例 :可输入Filippa Pettersson 或者 Cancer Res. 75(6) , 1102-12, (2015) 或者10.1002/anie.201600521

Thiadiazoles. I. Synthesis and Properties of [1, 2, 5] Thiadiazolo [3, 4-d] pyrimidines1

YF Shealy, JD Clayton…

文献索引：Shealy,Y.F. et al. Journal of Organic Chemistry, 1962 , vol. 27, p. 2154 - 2160

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被引用次数: 13

摘要

[1, 2, 5] Thiadiazolo [3, 4d] pyrimidines have been synthesized from 4, 5-diaminopyrimidines and N-sulfinylaniline. An intermediate in this reaction has been isolated. Replacement reactions have been observed to occur readily at position 7, and reductive cleavage of the thiadiazole ring has been demonstrated. Similarities in the properties of [1, 2, 5] thiadiazolo- [3, 4d] pyrimidines and pteridines have been noted. the pteridine^.^ Schrage and ...

2-巯基-4,5,6-三氨基嘧啶结构式

2-巯基-4,5,6-三氨基嘧啶

~%

[1,2,5]Thiadiazolo[3,4-d]pyrimidine-5(3H)-thione,7-amino-结构式

[1,2,5]Thiadiaz...

2-(甲硫基)嘧啶-4,5,6-三胺结构式

2-(甲硫基)嘧啶-4,5,6-三胺

~%

3-methylsulfanyl-8-thia-2,4,7,9-tetrazabicyclo[4.3.0]nona-2,4,6,9-tetraen-5-amine结构式

3-methylsulfany...

4,5-二氨基-6-巯基嘧啶结构式

4,5-二氨基-6-巯基嘧啶

~%

[1,2,5]Thiadiazolo[3,4-d]pyrimidine-7(3H)-thione结构式

[1,2,5]Thiadiaz...

4,5,6-Triamno-2-Methylpyrimidine结构式

4,5,6-Triamno-2...

~%

[1,2,5]Thiadiazolo[3,4-d]pyrimidin-7-amine, 5-methyl-结构式

[1,2,5]Thiadiaz...

6-morpholin-4-ylpyrimidine-4,5-diamine结构式

6-morpholin-4-y...

~%

[1,2,5]Thiadiazolo[3,4-d]pyrimidine,7-(4-morpholinyl)-结构式

[1,2,5]Thiadiaz...

2,4,5,6-四氨基嘧啶结构式

2,4,5,6-四氨基嘧啶

~%

8-thia-2,4,7,9-tetrazabicyclo[4.3.0]nona-2,4,6,9-tetraene-3,5-diamine结构式

8-thia-2,4,7,9-...

N4-phenylpyrimidine-4,5,6-triamine结构式

N4-phenylpyrimi...

~%

[1,2,5]Thiadiazolo[3,4-d]pyrimidin-7-amine, N-phenyl-结构式

[1,2,5]Thiadiaz...

6-氯嘧啶-4,5-二胺结构式

6-氯嘧啶-4,5-二胺

未登录结构式

~%

[1,2,5]Thiadiazolo[3,4-d]pyrimidin-7-amine, N-phenyl-结构式

[1,2,5]Thiadiaz...

6-benzylsulfanyl-pyrimidine-4,5-diamine结构式

6-benzylsulfany...

未登录结构式

~%

[1,2,5]Thiadiazolo[3,4-d]pyrimidin-7-amine, N-phenyl-结构式

[1,2,5]Thiadiaz...

未登录结构式

4,5-二氨基-6-巯基嘧啶结构式

4,5-二氨基-6-巯基嘧啶

~%

[1,2,5]Thiadiazolo[3,4-d]pyrimidin-7-amine, N-phenyl-结构式

[1,2,5]Thiadiaz...

4,5,6-三氨基嘧啶结构式

4,5,6-三氨基嘧啶

~%

[1,2,5]thiadiazolo[3,4-d]pyrimidin-7-amine结构式

[1,2,5]thiadiaz...

2-巯基-4-羟基-5,6-二氨基嘧啶结构式

2-巯基-4-羟基-5,6-二氨基嘧啶

~%

3-sulfanylidene-8-thia-2,4,7,9-tetrazabicyclo[4.3.0]nona-1,6-dien-5-one结构式

3-sulfanylidene...

N4,N4-dimethyl-pyrimidine-4,5,6-triamine结构式

N4,N4-dimethyl-...

~%

N,N-dimethyl-8-thia-2,4,7,9-tetrazabicyclo[4.3.0]nona-2,4,6,9-tetraen-5-amine结构式

N,N-dimethyl-8-...