Tetrahedron Letters

CuI/N, N-dimethylglycine-catalyzed synthesis of N-aryloxazolidinones from aryl bromides

J Li, Y Zhang, Y Jiang, D Ma

文献索引：Li, Jiaojiao; Zhang, Yihua; Jiang, Yongwen; Ma, Dawei Tetrahedron Letters, 2012 , vol. 53, # 31 p. 3981 - 3983

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被引用次数: 7

摘要

CuI/N, N-dimethylglycine catalyzed coupling of aryl bromides with substituted oxazolidinones took place at 120° C in DMF, affording the corresponding N-arylation products with good to excellent yields. A number of functional groups, such as ketone, nitrile, nitro, methoxy, and hydroxyl were tolerated under these conditions, thereby allowing diversity synthesis of N-aryloxazolidinones.