Tetrahedron

An efficient synthetic route to biologically relevant 2-phenylbenzothiazoles substituted on the benzothiazole ring

AA Weekes, MC Bagley, AD Westwell

文献索引：Weekes, Ashley A.; Bagley, Mark C.; Westwell, Andrew D. Tetrahedron, 2011 , vol. 67, # 40 p. 7743 - 7747

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被引用次数: 12

摘要

Certain 2-phenylbenzothiazoles containing substituents on the benzothiazole ring possess important biological properties, yet the majority of synthetic methods to 2- phenylbenzothiazoles described to date focus on their unsubstituted ring counterparts. Here we describe a new concise and efficient synthetic route to biologically relevant 2- phenylbenzothiazoles in high yield from the reaction of substituted 2-aminothiophenol ...