Abstract: Mono-and disubstituted acetylenes 5 are synthesized from carboxylic acid derivatives via the readily accessible@-keto sulfones 3. Reaction of esters, acid chlorides, and nitriles with lithiated derivatives of alkyl aryl sulfones affords the@ keto sulfones 3, which are converted to the enol phosphates 4 via the sodium or potassium enolates (Y= OEt, NMe2) or with catalysis by 4-dimethylaminopyridine (Y= OPh). Reductive elimination of ...
