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Regioselective multicomponent sequential synthesis of hydantoins

…, MC Bellucci, T Marcelli, A Volonterio

文献索引:Olimpieri, Francesca; Bellucci, Maria Cristina; Marcelli, Tommaso; Volonterio, Alessandro Organic and Biomolecular Chemistry, 2012 , vol. 10, # 48 p. 9538 - 9555

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被引用次数: 13

摘要

The development of new practical and green methods for the synthesis of small heterocycles is an attractive area of research due to the well-known potential of heterocyclic small molecule scaffolds in the drug discovery process. Herein we report a one-pot, three- component sequential procedure for the synthesis of diversely 1, 3, 5-and 1, 3, 5, 5- substituted hydantoins, in high yields and very mild conditions, using readily accessible ...