Investigational New Drugs 1996-01-01

A simplified and efficient synthesis of 5,10-dideaza-5,6,7,8-tetrahydrofolic acid (DDATHF).

E C Taylor, R Chaudhari, K Lee

文献索引：Invest. New Drugs 14(3) , 281-5, (1996)

全文：HTML全文

摘要

A new and extremely efficient synthesis of DDATHF from 4-vinylbenzoic acid and bromomalondialdehyde as precursors has been developed which proceeds in 48% overall yield.