Organic letters

NaIO4-mediated selective oxidative halogenation of alkenes and aromatics using alkali metal halides

GK Dewkar, SV Narina, A Sudalai

文献索引：Dewkar, Gajanan K.; Narina, Srinivasarao V.; Sudalai, Arumugam Organic Letters, 2003 , vol. 5, # 23 p. 4501 - 4504

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被引用次数: 114

摘要

NaIO4 oxidizes alkali metal halides efficiently in aqueous medium to halogenate alkenes and aromatics and produce the corresponding halo derivatives in excellent regio and stereoselectivity. The system also demonstrates the asymmetric version of bromo hydroxylation using β-cyclodextrin complexes, resulting in moderate ee.