Tetrahedron Letters

A novel ring cleavage reaction of oxazolines

JI Levin, SM Weinreb

文献索引：Levin, Jeremy I.; Weinreb, Steven M. Tetrahedron Letters, 1982 , vol. 23, # 23 p. 2347 - 2350

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被引用次数: 21

摘要

Oxazolines are now generally recognized as highly versatile synthons in organic chemistry. These readily available heterocycles are effective as carboxylic acid protecting groups,2 and as activators both for various metalation reactions 193 and for aromatic nucleophilic sub- stitutions. 4 Chiral oxazolines have recently played an important role in synthesis of many types of optically active compounds. 4c,d,5,6 ... An important feature of oxazolines is that they