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Adenylate Deaminase (5′??Adenylic Acid Deaminase, AMPDA)??Catalyzed Deamination of 5′??Deoxy??5′??Substituted and 5′??Protected Adenosines: A …

P Ciuffreda, A Loseto, L Alessandrini…

文献索引:Ciuffreda, Pierangela; Loseto, Angela; Alessandrini, Laura; Terraneo, Giancarlo; Santaniello, Enzo European Journal of Organic Chemistry, 2003 , # 24 p. 4748 - 4751

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被引用次数: 10

摘要

Abstract The enzyme adenylate deaminase (AMPDA) is able to catalyze the hydrolytic deamination of 5′-substituted and 5′-protected 5′-deoxyadenosines, whereas limited or no activity is shown by adenosine deaminase (ADA) towards the same substrates.(© Wiley- VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003)