Journal of medicinal chemistry

Some Alkylideneaminooxyalkanoic Acids and Derivatives1a

LH Klemm, DH Lee

文献索引：Klemm,L.H.; Hsu Lee,D. Journal of Medicinal Chemistry, 1966 , vol. 9, p. 435 - 436

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被引用次数: 0

摘要

In view of the interest in alkylideneaminooxyacetic acids and their esters as potential therapeutic agents2 and because of the use of alkylideneaminooxypropionic acid^^.^ in processes of optical resolutiona,5 and de- termination of absolute configuratioq6 we have now prepared additional homologs and their derivatives (I-IV) in this series. Several of these compounds have been tested for antitumor activity in the screening program of the Cancer Chemotherapy National ...