Tetrahedron letters

Palladium-catalyzed cross-coupling of trimethoxysilylbenzene with aryl bromides and chlorides using phosphite ligands

J Ju, H Nam, HM Jung, S Lee

文献索引：Ju, Jinhun; Nam, Hyungoog; Jung, Hyun Min; Lee, Sunwoo Tetrahedron Letters, 2006 , vol. 47, # 49 p. 8673 - 8678

全文：HTML全文

被引用次数: 42

摘要

Phosphites were employed as ligands in palladium-catalyzed Hiyama coupling reactions. The optimized reaction conditions were equimolar amounts (5mol% each) of Pd (acac) 2 and phosphite 1 in p-xylene at 80° C with TBAF as an additive. This catalyst system exhibited high activities in the reactions with trimethoxysilylbenzene and aryl bromides that have electron-donating or electron-withdrawing groups. In the case of aryl chlorides, ...