Reaction of [18F] 4??fluorobenzenediazonium cations with cysteine or the cysteinyl group: preparation of 18F??labeled S??aryl??cysteine and a radiolabeled peptide
JT Patt, M Patt
文献索引：Patt Journal of Labelled Compounds and Radiopharmaceuticals, 2002 , vol. 45, # 14 p. 1229 - 1238
Abstract A reaction route for the preparation of no-carrier-added (nca)[18 F] S-4- fluorophenylcysteine 7 via the [18 F]-4-fluorobenzenediazonium ion 4 is described. The key step in this radiosynthesis is the reaction of 4 with cysteine forming [18 F] 4- fluorophenyldiazocysteine 6, which is subsequently converted into 7 by irradiation with 366 nm light. 4 was synthesized by reacting 1, 4-dinitrobenzene 1 with [18 F]-fluoride in ...
