Antitumor agents. II. Bis (guanylhydrazones) of anthracene-9, 10-dicarboxaldehydes

KC Murdock, RG Child, YI Lin, JD Warren…

文献索引：Murdock; Child; Lin; Warren; Fabio; Lee; Izzo; Lang Jr.; Angier; Citarella; Wallace; Durr Journal of Medicinal Chemistry, 1982 , vol. 25, # 5 p. 505 - 518

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被引用次数: 64

摘要

Department of Chemical Research and Department of Chemotherapy Research, Infectious Disease Research Section, Medical Research Division, American Cyanamid Company, Lederle Laboratories, Pearl River, New York 10965. Received July 14, 1981 9, lO- Anthracenedicarboxaldehyde bis [(4, 5-dihydro-lH-imidazol-2-yl) hydrazone](bisantrene, VI- 1) showed anticancer activity in mice vs. both leukemias and solid tumors. Increases in life ...