Analogs of poison ivy urushiol. Synthesis and biological activity of disubstituted n-alkylbenzenes

MA ElSohly, PD Adawadkar, DA Benigni…

文献索引：ElSohly, Mahmoud A.; Adawadkar, Prakash D.; Benigni, Daniel A.; Watson, Edna S.; Little, Thomas L. Journal of Medicinal Chemistry, 1986 , vol. 29, # 5 p. 606 - 611

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被引用次数: 22

摘要

The total synthesis of different isomers and analogues of poison ivy urushiol is described. These include the positional isomers 1-5 and the nitrogen-containing analogues 6 and 8 and their mesylamino derivatives 7 and 9. 3, 4-Dimethoxybenzaldehyde, m- dimethoxybenzene, resorcinol, and p-dimethoxybenzene were used as starting materials for compounds 1, 2, 3, and 4, respectively. Compound 5 is prepared by catalytic ...