Discovery of highly potent and selective benzyloxybenzyl-based peroxisome proliferator-activator receptor (PPAR) δ agonists

LD Bratton, GF Filzen, A Geyer, JK Hoffman…

文献索引：Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 13 p. 3624 - 3629

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被引用次数: 8

摘要

... Bioorganic & Medicinal Chemistry Letters. ... Targets 13h and 13i were synthesized by a different route in an effort to prepare a common intermediate two steps away from the desired targets and to facilitate purification in a parallel chemistry strategy (Scheme 2). The alternative ...