NHC-Pd complex-catalyzed double carbonylation of aryl iodides with secondary amines to α-keto amides

S Zheng, Y Wang, C Zhang, J Liu…

文献索引：Zheng, Shuzhan; Wang, Yan; Zhang, Chunyan; Liu, Jianhua; Xia, Chungu Applied Organometallic Chemistry, 2014 , vol. 28, # 1 p. 48 - 53

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被引用次数: 14

摘要

A series of palladium–NHC compounds were prepared and their catalytic activity in the double carbonylation of aryl iodides to synthesize α-keto amides were examined. Palladium complexes bearing mixed NHC–phosphine exhibited high efficiency for the double carbonylation reaction. The effects of different solvents, base, temperature, carbon monoxide (CO), pressure, various amine and aryl iodides were investigated. Both electron-rich and ...