Methods for the synthesis of 9 new compounds have been developed. These substances were called aggregate analogs because they were constructed by union of appropriate analogs of 2 distinct essential metabolites, viz., p-aminobenzoic acid and 1, 2-dimethyl-4, 5- diaminobenzer1e. These aggregate analogs M ere conceived as a means of realizing new pharmacological agents of high potency, and with a type of action which would not be ...